Showing : Big Data • reset
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Job: Postdoc and PhD student in Bioinformatics/Biostatistics
NGS R statistics genomics big data Job
6.9 years ago • updated 6.1 years ago Luo Weijun ★ 1.6k
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Job: Data Manager - BC Cancer Research Center, Vancouver BC
computational genomic big data bioinformatics Job
6.6 years ago jmaanaki • 0
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Job: Postdoctoral positions in drug discovery and genome data science
computational biology biostatistics big data data science drug discovery Job
6.9 years ago Thomas Girke ★ 1.7k
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How to handle big data sets (>10GB) in Bioconductor packages?
big data methylmix memory problem
updated 7.4 years ago by 25k • written 7.4 years ago by • 0
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Subsetting Rle with ORF-sequence-positions by the 3 frames
Rle Big data coverageByTranscript
7.8 years ago • updated 7.7 years ago hauken_heyken ▴ 80
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What is the recommended method for running WGCNA on large metatranscriptomic dataset?
wgcna transcriptome big data metagenomics gene expression
7.9 years ago jol.espinoz ▴ 40
3
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1.8k
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AnnotationHub: confusing pValue/qValue for (some) Roadmap records
roadmap project annotationhub epigenomics big data
updated 9.7 years ago by ★ 6.8k • written 9.7 years ago by ▴ 350
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Job: Postdoctoral Research Associate Position- Harvard Medical School (Probabilistic Algorithms and Software for Biomedical Big Data)
Probabilistic Algorithms Big Data Job
10.7 years ago Doe, Aimee ▴ 40
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Comment: DESeq2 - how many surrogate variables from svaseq, use of lfcshrink by ja569116 • 0
Hi @atpoint Thanks for the information. Could you please expand on when to use adjusted p-values vs nominal p-values. My understanding was …
Answer: limpa analysis advice by Gordon Smyth 53k
It is actually very hard to estimate the DPC from observed data, because the curve is function of unobserved intensities rather than a func…
Answer: When to use edgeR or limma by Gordon Smyth 53k
The short answer is that we generally prefer edgeR for applications with lots of small counts and limma for complex designs with random eff…
Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry by Gordon Smyth 53k
I updated the above answer today.
Answer: When to use edgeR or limma by James W. MacDonald 68k
I would use edgeR's quasi-likelihood model for any analysis with a smaller number of observations (like 3 vs 3 or similar), but if you have…
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Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
A: deseq2 - paired samples in 2 sequencing types with very different library sizes
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