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1.5k

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NGS R statistics genomics big data Job

5.9 years ago • updated 5.1 years ago Luo Weijun ★ 1.6k

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computational genomic big data bioinformatics Job

5.6 years ago jmaanaki • 0

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computational biology biostatistics big data data science drug discovery Job

5.9 years ago Thomas Girke ★ 1.7k

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big data methylmix memory problem

updated 6.3 years ago by Martin Morgan 25k • written 6.3 years ago by perdedorium • 0

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Rle Big data coverageByTranscript

6.7 years ago hauken_heyken ▴ 80

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wgcna transcriptome big data metagenomics gene expression

6.9 years ago jol.espinoz ▴ 40

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roadmap project annotationhub epigenomics big data

updated 8.7 years ago by Valerie Obenchain ★ 6.8k • written 8.7 years ago by kevin.rue ▴ 350

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Probabilistic Algorithms Big Data Job

9.7 years ago Doe, Aimee ▴ 40

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Comment: Incorporating Salmon offset matrix into Wilcoxon DEG analysis by Gordon Smyth 52k

Sorry, I cannot follow what you're saying. The two code sequences you show look to be exactly the same.

Answer: Mean variance curve troubleshoot filtering by Gordon Smyth 52k

You could use `filterByExpr()`, as recommended by Law et al (2018) and in the limma and edgeR case studies. However, the main problem wi…

Comment: How do I fix an odd voom plot in a combined dataset? by Gordon Smyth 52k

The fact that you have partial NA coefficients indicates that your merged dataset consists in good part of NAs for a very large number of g…

Comment: How do I fix an odd voom plot in a combined dataset? by 1sunmic2 • 0

Thanks for responding! I did change the code slightly: dge1 <- DGEList(counts = combined_data_counts) keep <- rowSums(cpm(dge1)…

Comment: Incorporating Salmon offset matrix into Wilcoxon DEG analysis by Andre • 0

The estimateGLMRobustDisp() function seems to have an effect on glmQLFit(), even in edgeR 4 (4.4.1). If I use estimateGLMRobustDisp(), like…

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Answer: How do I fix an odd voom plot in a combined dataset?

Comment: How do I fix an odd voom plot in a combined dataset?

C: How does edgeR cpm function calculate log(CPM) values?

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